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Mankind is facing an epidemic of non-infectious diseases that is threatening
to lower the life expectancy of the present generation. Many diseases are
unique to the developed world and are fast increasing in the developing world
as well. Obesity, diabetes mellitus, high blood pressure, atherosclerotic
vascular disease and related problems like heart attack and stroke, cancers,
osteoporosis etc. are termed as Diseases of Civilisation. [1,2] Many of these
disorders are identified as components of the metabolic syndrome [3,4] and has
been related to increased levels of insulin (Hyperinsulinemia)
in the blood and insulin resistance (also called Insulin Resistance
Syndrome)[5-10]
Components of
Metabolic Syndrome:[3,4]
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Central obesity
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Hyperleptinemia
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Hyperinsulinemia
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Resistance to insulin-stimulated glucose uptake
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Glucose intolerance - Type 2 Diabetes mellitus
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Hypertension
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Hepatic steatosis (non-alcoholic)
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Polycystic ovary syndrome
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Hyperuricemia
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Post-prandial lipemia
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High levels of small dense low-density lipoprotein
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High levels of very low-density lipoprotein triglyceride
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Low levels of high-density lipoprotein cholesterol
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High levels of plasminogen activator inhibitor-1
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Endothelial dysfunction
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Hyperactive sympathetic nervous system
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High intra-myocellular lipids
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Sub-clinical inflammation
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Low levels of serum adiponectin
If all these disorders are related to increased levels and
abnormal functioning of the hormones of insulin and leptin, it is obvious that
these can be managed by bringing these hormones back to normal and making them
functional again. That indeed is the key to health and longevity. Where is the
need for medications for each one of these problems?
Spandana Centre For Metabolic Medicine offers
State-Of-Science facilities for clinical and laboratory assessment of these
disorders and provides dietary and lifestyle guidelines for managing these
disorders so as to regain your health, Naturally!
References
- Sergey Komarov. Mankind Is Predisposed To Diseases Of Civilization. At
http://www.medicalnewstoday.com/articles/29755.php
-
Moss RW. Cancer: A Disease of Civilization?
At
http://www.newagejournal.com/moss.shtml
-
Misra A, Vikram NK. Insulin resistance syndrome (metabolic
syndrome) and Asian Indians.
Current Science 2002;83(12) At
http://www.iisc.ernet.in/currsci/dec252002/1483.pdf
- Rao G. Insulin Resistance Syndrome American
Family Physician. 2002;63(6) At
http://www.aafp.org/afp/20010315/1159.html
- Metabolic syndrome At
http://www.mayoclinic.com/health/metabolic%20syndrome/DS00522
- Metabolic
Syndrome At
http://www.americanheart.org/presenter.jhtml?identifier=4756
- Metabolic Syndrome Simplified At
http://www.metabolicsyndrome.org.uk/Simplified/default.htm
-
Ferrannini E, Haffner SM,
Mitchell BD, Stern MP. Hyperinsulinaemia: the key feature of a cardiovascular and metabolic
syndrome. Diabetologia. 1991;34(6)::416-422
Abstract At
http://www.springerlink.com/content/q41268052426733h/
- Diagnosis and Management of the Metabolic Syndrome: An American Heart Association/National Heart, Lung, and Blood Institute
Scientific Statement At
http://circ.ahajournals.org/cgi/content/full/112/17/2735
-
Bloomgarden ZT.
Definitions of the Insulin Resistance Syndrome: The 1st World Congress on
the Insulin Resistance Syndrome
Diabetes Care
2004;27:824-830 At
http://care.diabetesjournals.org/cgi/content/full/27/3/824
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First Such Facility
In India |
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Chief Mentor and
Consultant Physician Dr. B. Srinivas Kakkilaya,
M.D. |
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Consultant
Dermatologist Dr. Balasaraswathy P.,
D.N.B., D.V.D. |
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Consultant Biochemist Mr. Aravind Rao,
M.Sc. |
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Burn Your Fat, Lose Weight, Live Longer! |
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